Principal Scientist/Associate Director- Antibody discovery
NovaRock Biotherapeutics is a dynamic start-up company dedicated to the discovery, development, and commercialization of potentially transformative therapeutics for the treatment of cancer, autoimmune and other diseases. We offer a technologically and scientifically rigorous environment with all the fun and passion that a start-up provides, plus a competitive compensation package including excellent benefits.
We seek a highly motivated and energetic Principal Scientist/Associate Director with strong scientific background and expertise in antibody discovery and characterization to join our antibody discovery team at the central New Jersey site.
Responsibilities
- Provide therapeutic antibody discovery and characterization strategies
- Manage scientists and lead the team to screen and deliver antibody candidates
- Uses Tecan or other automation platforms to screen and discover antibodies efficiently
- Provide strategies for high throughput antibody screening from hybridomas, single B cell cloning and display platforms
- Lead the team to conduct antibody characterization (SDS PAGE, ELISA, Octet)
- Data analysis, report writing, presentation at project team meetings
- Collaborate with internal scientific functions and enable cross-functional project teams
- Lead scientific programs from antibody discovery, characterization, development to IND filing
Qualifications
- MS or PhD in molecular biology, biochemistry or related fields
- Strong organization and people managerial skills
- Extensive experience in antibody discovery and characterization
- Experience with antibody V gene capture and display technologies
- Experience with FACS target B-cell sorting or selection
- Experience in molecular biology, PCR, antibody cloning and expression
- Experience with Octet or related technology platforms is desirable
- Experience with antibody purification and bioanalytical is a plus
- Good communication skills are required
- Experience in biotech or pharmaceutical industry research is desirable
- Proven tracked records of scientific accomplishments